Baicalin

Best

Antioxidant

Baicalin at a glance

  • Type of flavonoid
  • Derived from Scutellaria baicalensis plant
  • Rich in antioxidants
  • Has anti-inflammatory properties
  • May play a role in skin’s youthful longevity

Baicalin description

Baicalin is a flavonoid (a compound produced as part of plants’ metabolic processes) derived mostly from the _Scutellaria baicalensis_ (Chinese skullcap) plant, whose root has been used for years in Traditional Chinese Medicine. As a flavonoid, baicalin is a good source of antioxidants to protect against oxidative stress. Research also shows that it has anti-inflammatory properties. One study found it helped specifically relieve skin inflammation caused by P. acnes bacteria, the main bacterial culprit behind acne breakouts. Baicalin may also play a role in maintaining skin’s healthspan by interrupting intrinsic aging factors that hinder youthful longevity. Studies have found that baicalin can delay UVA-induced photoaging through the inhibition of oxidative damage by selectively neutralizing super-oxide anion and regulation of some of the senescence-related genes. The independent Cosmetic Ingredient Review has ruled baicalin safe as used in cosmetics. Use levels of baicalin in skin care range from 1–1.5% when the plant extract is part of a water-based blend.

Baicalin references

  • Journal of Photochemistry and Photobiology B: Biology, July 2024, ePublication
  • ACS Omega, October 2023, pages 40,260–40,276
  • International Journal of Molecular Sciences, December 2022, pages 1-12
  • Bioorganic Chemistry, February 2022, ePublication
  • International Journal of Molecular Sciences, June 2021, pages 1–18
  • Brazilian Journal of Medical and Biological Research, October 2020, pages 1-10
  • Cosmetic Ingredient Review, Website, September 2020

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.